| 11. Runde | ||||||||
|---|---|---|---|---|---|---|---|---|
| 03.05.2021 | 23:00 | Montevideo Wanderers | Montevideo Wanderers | - | Montevideo bymoment | Montevideo bymoment | -: - | |
| 03/06/2021 | 20:15 | Boston River | Boston River | - | CA Cerro | CA Cerro | -: - | |
| 03/06/2021 | 23:15 | Peñarol | Peñarol | - | elveplate | elveplate | -: - | |
| 03/07/2021 | 19:30 | Donau | Donau | - | Liverpool | Liverpool | -: - | |
| 03/07/2021 | 21:45 | Cerro Largo | Cerro Largo | - | Colonia Square | Colonia Square | -: - | |
| 03.08.2021 | 00:45 | nasjonal | nasjonal | - | Defender Sporting | Defender Sporting | -: - | |
| 03.08.2021 | 19:30 | Rentistas | Rentistas | - | Framgang | Framgang | -: - | |
| 03.08.2021 | 21:45 | Deportivo Maldonado | Deportivo Maldonado | - | Føniks | Føniks | -: - | |
| 12. Runde | ||||||||
| 03/06/2021 | Liverpool | Liverpool | - | elveplate | elveplate | resch. | ||
| 03/06/2021 | Montevideo bymoment | Montevideo bymoment | - | Peñarol | Peñarol | resch. | ||
| 03/06/2021 | Colonia Square | Colonia Square | - | Montevideo Wanderers | Montevideo Wanderers | resch. | ||
| 03/06/2021 | Framgang | Framgang | - | Cerro Largo | Cerro Largo | resch. | ||
| 03/06/2021 | Føniks | Føniks | - | Rentistas | Rentistas | resch. | ||
| 03/06/2021 | CA Cerro | CA Cerro | - | Deportivo Maldonado | Deportivo Maldonado | resch. | ||
| 03/06/2021 | Defender Sporting | Defender Sporting | - | Boston River | Boston River | resch. | ||
| 03/06/2021 | Donau | Donau | - | nasjonal | nasjonal | resch. |
| | | |
