| 15. Runde | ||||||||
|---|---|---|---|---|---|---|---|---|
| 03/10/2021 | 15:00 | Kong Faisal | Kong Faisal | - | Asante Kotoko | Asante Kotoko | -: - | |
| 17. Runde | ||||||||
| 03.05.2021 | 15:00 | Interallierte | Interallierte | - | Ashanti Gold | Ashanti Gold | -: - | |
| 03.05.2021 | 18:00 | Elmina Sharks | Elmina Sharks | - | Asante Kotoko | Asante Kotoko | -: - | |
| 03/06/2021 | 15:00 | Karela FC | Karela FC | - | Tollstjerner | Tollstjerner | -: - | |
| 03/06/2021 | 15:00 | Kong Faisal | Kong Faisal | - | Liberty Professionals | Liberty Professionals | -: - | |
| 03/07/2021 | 15:00 | Bechem United | Bechem United | - | Ebusua Dverger | Ebusua Dverger | -: - | |
| 03/07/2021 | 15:00 | Berekum Chelsea | Berekum Chelsea | - | Medeama SC | Medeama SC | -: - | |
| 03/07/2021 | 15:00 | Dreams FC | Dreams FC | - | Flott OL | Flott OL | -: - | |
| 03/07/2021 | 15:00 | Elleve underverk | Elleve underverk | - | Legon Cities | Legon Cities | -: - | |
| 03/07/2021 | 15:00 | Hearts of Oak | Hearts of Oak | - | WAFA | WAFA | -: - | |
| 18. Runde | ||||||||
| 20.03.2021 | 15:00 | Bechem United | Bechem United | - | Liberty Professionals | Liberty Professionals | -: - | |
| 20.03.2021 | 15:00 | Berekum Chelsea | Berekum Chelsea | - | Legon Cities | Legon Cities | -: - | |
| 20.03.2021 | 15:00 | Dreams FC | Dreams FC | - | Interallierte | Interallierte | -: - | |
| 20.03.2021 | 15:00 | Elleve underverk | Elleve underverk | - | Asante Kotoko | Asante Kotoko | -: - | |
| 20.03.2021 | 15:00 | Elmina Sharks | Elmina Sharks | - | Ebusua Dverger | Ebusua Dverger | -: - | |
| 20.03.2021 | 15:00 | Flott OL | Flott OL | - | Medeama SC | Medeama SC | -: - | |
| 20.03.2021 | 15:00 | Hearts of Oak | Hearts of Oak | - | Tollstjerner | Tollstjerner | -: - | |
| 20.03.2021 | 15:00 | Karela FC | Karela FC | - | Ashanti Gold | Ashanti Gold | -: - | |
| 20.03.2021 | 15:00 | Kong Faisal | Kong Faisal | - | WAFA | WAFA | -: - |
| | | |
