| 1. Runde | ||||||||
|---|---|---|---|---|---|---|---|---|
| 03/04/2021 | 01:05 | Patriots FC | Patriots FC | - | Amerika fra Cali | Amerika fra Cali | 0: 1 (0: 0) | |
| 2. Runde | ||||||||
| 03/04/2021 | 23:00 | Boyacá Chicó | Boyacá Chicó | - | Millionærer | Millionærer | 0: 1 (0: 0) | |
| 03.05.2021 | 01:05 | Santa Fe | Santa Fe | - | Sports Tolima | Sports Tolima | 3: 2 (1: 0) | |
| 10. Runde | ||||||||
| 03.03.2021 | 01:00 | National Athletic | National Athletic | - | Petroleum Alliance | Petroleum Alliance | 5: 0 (2: 0) | |
| 11. Runde | ||||||||
| 03.05.2021 | 23:00 | Uavhengig Medellin | Uavhengig Medellin | - | Egenkapital | Egenkapital | -: - | |
| 03/06/2021 | 01:00 | Atlético Junior | Atlético Junior | - | Atletisk Bucaramanga | Atletisk Bucaramanga | -: - | |
| 03/06/2021 | 22:30 | En gang Caldas | En gang Caldas | - | Deportivo Cali | Deportivo Cali | -: - | |
| 03/07/2021 | 01:00 | Rionegro Golden Eagles | Rionegro Golden Eagles | - | National Athletic | National Athletic | -: - | |
| 03/07/2021 | 20:30 | Amerika fra Cali | Amerika fra Cali | - | Deportivo Pereira | Deportivo Pereira | -: - | |
| 03/07/2021 | 22:40 | Jaguarer fra Cordoba | Jaguarer fra Cordoba | - | Patriots FC | Patriots FC | -: - | |
| 03.08.2021 | 01:00 | Boyacá Chicó | Boyacá Chicó | - | Sports Tolima | Sports Tolima | -: - | |
| 03/09/2021 | 01:00 | Santa Fe | Santa Fe | - | Deportivo Pasto | Deportivo Pasto | -: - | |
| 03/10/2021 | 01:00 | Petroleum Alliance | Petroleum Alliance | - | Millionærer | Millionærer | -: - | |
| 12. Runde | ||||||||
| 03/14/2021 | Rionegro Golden Eagles | Rionegro Golden Eagles | - | Uavhengig Medellin | Uavhengig Medellin | -: - | ||
| 03/14/2021 | National Athletic | National Athletic | - | Atlético Junior | Atlético Junior | -: - | ||
| 03/14/2021 | Atletisk Bucaramanga | Atletisk Bucaramanga | - | En gang Caldas | En gang Caldas | -: - | ||
| 03/14/2021 | Deportivo Cali | Deportivo Cali | - | Amerika fra Cali | Amerika fra Cali | -: - | ||
| 03/14/2021 | Egenkapital | Egenkapital | - | Envigado FC | Envigado FC | -: - | ||
| 03/14/2021 | Deportivo Pasto | Deportivo Pasto | - | Petroleum Alliance | Petroleum Alliance | -: - | ||
| 03/14/2021 | Patriots FC | Patriots FC | - | Millionærer | Millionærer | -: - | ||
| 03/14/2021 | Deportivo Pereira | Deportivo Pereira | - | Boyacá Chicó | Boyacá Chicó | -: - | ||
| 03/14/2021 | Sports Tolima | Sports Tolima | - | Jaguarer fra Cordoba | Jaguarer fra Cordoba | -: - |
| | | |
